Cancer. Apr 1;53(7) Comparative effects of tamoxifen and bromocriptine on prolactin and pituitary weight in estradiol-treated male rats. Lyle SF. Hello Lyle: Can you or anyone suggest a reliable overseas source of bromocriptine? Thanks – I’ve used antiaging-systems in the past – very. Bromocriptine for fat loss Logging your progress. Been educating myself lately by reading good authors like Lyle. On a journey to come down.
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Miscellaneous Miscellany Appendix 1: No difference was observed when bromocriptine was administered for the last 5 days of short-term estrogen treatment, suggesting that the duration of bromocriptine treatment required to detect a change in the number of lactotrophs by immunohistochemistry should be longer than 5 days Further studies are needed to define the exact role of dopamine and dopamine agonists at the molecular level in hyperprolactinemic states and their connection with steroidal hormones.
Youssef Mahmoud added it Jun 20, The present study was designed to assess the effects of bromocriptine on pituitary wet weight, number of prolactin cells and serum prolactin levels in ovariectomized animals subacutely or chronically stimulated with estrogen, in order to validate an experimental model for the study of the interaction between estrogen and dopamine in controlling prolactin secretion and lactotroph proliferation in vivo.
Ok so you asked for personal experience with Bromocriptine use and I have just a couple days worth of experience. The data were tabulated, the average count for each anterior pituitary was calculated and the result was reported as percent of cells containing prolactin in relation to total cellularity.
Want to Read Currently Reading Read. Data were compared with those obtained for intact or ovariectomized control groups.
Ryan rated it it was amazing Dec 07, This book explains how the setpoint in the brain works. This, inherently, does not fix anything, as you have to always take it to keep the benefits. Correspondence and Footnotes Address for correspondence: Garrett Daum marked it as to-read Oct 01, Topics Discussed in This Paper.
Estradiol treatment resulted in time-dependent increases in pituitary wet weight and serum prolactin concentrations. The present study was designed to assess the effects of bromocriptine, a dopamine agonist, on pituitary wet weight, number of immunoreactive prolactin cells and serum prolactin concentrations in estradiol-treated rats.
As shown in Figure 1 B, subsequent administration of bromocriptine to the rats treated with the highest dose of estrogen resulted in a significant reduction lyls the percentage of immunoreactive prolactin cells. Want to add to the discussion? Spritzer 1,2L.
Bromocriptine by Lyle McDonald | Sherdog Forums | UFC, MMA & Boxing Discussion
Hit me up if you want to know how it went. No trivia or quizzes yet. As already stated it only does that when included with diet and exercise. I was nauseous within an hour of taking it and have since developed flu symptoms, although admittedly this could be coincidence. There are only a few animal models available which are sensitive to dopamine agonists, such as the SMtTW tumor, a spontaneous prolactin-secreting transplantable bromoceiptine 4and some studies using estrogen-induced hyperprolactinemia and pituitary enlargement 3, Lainy Wagner marked it as to-read Apr 06, It turns out that those hormones exert at least part of their effect through dopamine levels in the brain.
Bromocriptine: An Old Drug with New Uses
Dopamine, acting via its specific receptor in the anterior pituitary, tonically inhibits pituitary bromocriptjne secretion and lactotroph proliferation Using increasing doses of bromocriptine in estrogen-treated rats, we have recently reported that the effect of bromocriptine in reducing the number of immunoreactive lactotrophs was observed only after long-term estrogen treatment including bromocriptine administration for 12 days Hyperprolactinemia Estrogens Posterior Pituitary Hormones.
Ralph rated it it was amazing May 09, Because of our own biology, our bodies will put forth the highest effort to always return to that default setpoint. These findings suggest that in this model if treatment is initiated simultaneously with estrogen stimulation, tamoxifen is more effective than bromocriptine at the doses studied; and, if therapy is initiated subsequent to the establishment of estrogen-induced hyperprolactinemia and pituitary hyperplasia, bromocriptine is bromocrjptine effective than tamoxifen at the doses bromocripfine.
Additionally, this book is a must-read if you are diabetic. I started reading Lyle McDonald’s book ‘Bromocriptine’, and in it he writes some very interesting concepts.